Daminozide
货号：
14058 基本售价：
2030.0 元 规格：
250 mg
产品信息
概述| 货号 | 14058 |
| 描述 | A selective inhibitor of the KDM2/7 JmjC subfamily of histone demethylases. IC50 = 1.5, 0.55 and 2.1 µM for KDM2A, PHF8 and KDM7A respectively. Highly selective over other subfamily members (KDM3, KDM4, KDM5 and KDM6) as well as other 2-oxoglutarate oxygenases (FIH, PHD2 and BBOX1), IC50 > 100 M (ref 1). |
| 别名 | 1-(2,2-Dimethylhydrazide)butanedioic acid; N-(dimethylamino)succinamic acid |
性能| 供应商 | Active Motif |
| 运输条件 | Blue Ice |
| 存放说明 | Store desiccated as supplied at room temperature for up to 3 years. Store solutions at -20°C for up to 3 months. |
| 纯度 | MP = 158-162°C>98% (TLC); NMR (Conforms) |
| 计算分子量 | 160.2 |
| 分子式 | C6H12N2O3 |
| CAS号 | 1596-84-5 |
| 外观 | White powder. May be dissolved in DMSO (50 mg/ml); Water (20 mg/ml, warm). |
| 参考文献 | 1. NR Rose et al. J. Med. Chem. 2012, 55:6639
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参考图片Chemical structure of Daminozide. |
