SNAP-25 Pure 20/SNAP-25 50ug
货号:
610366 基本售价:
4140.0 元 规格:
50ug
产品信息
概述货号 | 610366 |
描述 | Release of neurotransmitters from neurons is regulated by exocytosis of synaptic vesicles. This exocytosis is mediated by a complex consisting of membrane components of both the synaptic vesicle and the synaptic plasma membrane. The fusion complex consists of the soluble NSF (N-ethyl-maleimide-sensitive factor) and SNAPs (soluble NSF attachment proteins), along with the receptor proteins (known as SNAREs) synaptobrevin, synaptotagmin, syntaxin, and SNAP-25 (synaptosomal-associated protein of 25 kDa- the name is coincidental to the previously mentioned “SNAP” terminology). SNAP-25 and syntaxin are plasmalemmal proteins (designated as t-SNAREs) while synaptobrevin and synaptotagmin are vesicular proteins (designated as v-SNAREs). These four proteins are thought to constitute an initial SNARE docking complex for regulated exocytosis. SNAP-25 lacks a transmembrane domain, but is linked to the membrane by palmitoylated cysteine residues in the central region of the molecule. |
别名 | Synaptosomal Associated Protein of 25 kD |
同种亚型 | IgG1 |
反应种属 | Rat (QC Testing) Mouse (Tested in Development) |
来源宿主 | Mouse |
使用方法 | WB, IF |
性能供应商 | BD Pharmingen |
免疫原 | Mouse SNAP-25 aa. 8-29 |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
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存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |