Nischarin Pure 50 100ug
货号：
558262 基本售价：
3752.0 元 规格：
100ug
产品信息
概述| 货号 | 558262 |
| 描述 | Integrins are membrane receptors that mediate cell-cell or cell-matrix adhesion. All integrins are transmembrane heterodimers composed of αandβ subunits which are connected to the cytoskeleton. At least 20 integrins, formed from combinations of the 12 α and 9 β subunits, have been reported. Many of these have been implicated as transducers of molecular signals. Their roles are essential for embryonic development, tumor metastasis, cell motility, organ function, and proper immune cell function. Nischarin is a novel protein that binds, through its 464-562 amino-acid region, to the cytoplasmic domain of integrin α5. Expression of Nischarin is abundant in many tissues, especially brain and kidney, and its mRNA can be detected as early as day 7 in the mouse embryo. Nischarin might act as a negative regulator of cell migration by inhibiting Rac function. Nischarin has a predicted molecular weight of 148 kDa (NiceProt:Q9EPW8), although we detect it at 215 kDa in SDS/PAGE. mAb 50 reacts with Nischarin in rat (routinely tested for each lot), human (tested in development only), and mouse (tested in development only) tissue. |
| 同种亚型 | IgG1 |
| 反应种属 | Rat (QC Testing) Human, Mouse (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse Nischarin |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
