SCP3 Pure 25/SCP3 50ug
货号：
611230 基本售价：
3726.0 元 规格：
50ug
产品信息
概述| 货号 | 611230 |
| 描述 | Division of haploid germ cells during meiosis involves the pairing and recombination of homologous chromosomes. The synaptonemal complex (SC) is a meiotic protein structure that enhances chromosome pairing and segregation, affects the number and distribution of crossovers, and produces functional chiasmata from crossovers. The SC contains a central element (CE) and two lateral elements (LE) that are connected by transverse filaments (TF). Among the various SC components are two mammalian LE proteins, SCP2 and SCP3 (Synaptonemal Complex Proteins 2 and 3). SCP3 is highly similar to two other mammalian proteins, Xlr and Xmr, that are expressed in B and T lymphocytesand meiotic cells, respectively, and to members of the IF (intermediate filament) protein family. The SCP3 C-terminal region contains multiple coiled-coil domains that mediate protein-protein interactions. Via these domains, SCP3 self-assembles into transversely striated homopolymeric fibers in somatic cells. Such assembly also requires the N-terminal nonhelical domain. This function indicates that SCP3 may serve as an LE molecular scaffold to which other proteins bind and participate in recombination. |
| 别名 | Synaptonemal Complex Protein-3 |
| 同种亚型 | IgG1 |
| 反应种属 | Rat (QC Testing) Human, Mouse, Dog, Chicken (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Rat SCP3 aa. 1-109 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
