PNUTS Pure 47PNUTS 50ug
货号：
611060 基本售价：
3726.0 元 规格：
50ug
产品信息
概述| 货号 | 611060 |
| 描述 | Many aspects of cellular physiology are influenced by the serine/threonine protein phosphatase1 (PP1). It is a highly conserved eukaryotic protein that reverses the action of protein kinases. PP1 is key to such processes as cell division, neuronal metabolism, and protein synthesis. It consists of a catalytic subunit, with a broad substrate specificity, whose action is directed by its association with a family of regulatory proteins including inhibitor-1, inhibitor-2, and NIPP-1. In response to extracellular stimuli, these proteins interact with PP1 and inhibit its catalytic activity. Other regulatory proteins are referred to as targeting subunits because they direct PP1 to specific subcellular locations and modulate its activity. In the cell nucleus, PP1 has been implicated in a variety of processes. Nuclear PP1 exists in high MW complexes with other proteins including NIPP-1. PNUTS (phosphatase 1 nucleartargetingsubunit) is a ubiquitously expressed nuclear protein that forms a stable complex with PP1 and is thought to modulate its catalytic activity. Thus, PNUTS is a specific regulatory protein that directs the nuclear function of PP1. |
| 同种亚型 | IgG1 |
| 反应种属 | Rat (QC Testing) Human, Mouse (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Rat PNUTS aa. 605-716 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
