MKP2 Pure 48/MKP2 50ug
货号：
610850 基本售价：
3726.0 元 规格：
50ug
产品信息
概述| 货号 | 610850 |
| 描述 | The mitogen activated protein (MAP) kinases mediate signal transduction pathways involved in cellular growth and differentiation. These MAP kinases, including ERK1 and ERK2, are activated by phosphorylation on Tyr and Thr by MEK (MAP and ERK Kinase). Regulation of the resulting physiological effects of MAP Kinase activation is affected in part by MAPKinasep hosphatases (MKPs). These phosphatases have dual specificity, dephosphorylating both the tyrosine and threonine residues on MAP kinases. MKP2, which is widely expressed in human tissues, specifically dephosphorylates activated ERKs and JNK. These phosphatases have overlapping substrate specificities for the three known families of MAP kinases - p38, ERK, and JNK. All of the known MKPs contain a highly conserved carboxyl-terminal catalytic domain flanked by two CH2 (CDC25 homology 2) domains. |
| 同种亚型 | IgG1 |
| 反应种属 | Rat (QC Testing) Human, Mouse, Frog (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Rat MKP2 aa. 13-127 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
