Synapsin IIa Pure 1/Synapsin IIa 50ug
货号：
610666 基本售价：
3726.0 元 规格：
50ug
产品信息
概述| 货号 | 610666 |
| 描述 | Synapsins are a group of four related proteins (synapsin Ia, Ib, IIa, and IIb) found exclusively in neuronal tissues. The four identified synapsins originate by alternative splicing of the mRNA from two different genes (synapsin I and II). Phosphorylation of synapsins occurs concomitantly with membrane excitation and neurotransmitter release into the synaptic cleft. Synapsins bind to the synaptic vesicles through their amino terminal domain, which also contains phosphorylation sites for the cAMP-dependent protein kinase. In vitro, synapsins bundle actin filaments. This indicates that synapsins may cross-link the vesicles with the actin filaments at the presynaptic terminal. By using hippocampal neurons and specific anti-sense oligonucleotides to block synapsin IIa expression, it was found that synapsin IIa was essential for the formation of synapses. |
| 同种亚型 | IgG1 |
| 反应种属 | Rat (QC Testing) Human (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IHC, IP, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Rat Synapsin IIa aa. 451-586 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
