LRP Pure 42/LRP 50ug
货号:
610512 基本售价:
3726.0 元 规格:
50ug
产品信息
概述货号 | 610512 |
描述 | Drugs that selectively attack dividing cells are often used in cancer therapy. However, small cell populations do not die, but develop resistance to a variety of toxic drugs. Multidrug resistance is achieved by gene amplification of specific membrane-bound transport ATPases that shuttle the drugs out of cells. Some multidrug-resistant cancer cells express a protein of 110 kDa named LRP (LungResistance-relatedProtein). LRP expression might be an indicator of prognosis after chemotherapy in acute myeloid leukemia and ovarian carcinoma. The LRP gene encodes a protein of 896 amino acids with significant homology to the major vault protein from Dictyostelium discoideum. Although ubiquitously expressed, LRP is most abundant in epithelial cells. |
同种亚型 | IgG1 |
反应种属 | Human (QC Testing) Dog, Rabbit, Cow (Tested in Development) |
来源宿主 | Mouse |
使用方法 | WB, IHC, IP, IF |
性能供应商 | BD Pharmingen |
免疫原 | Human LRP aa. 403-592 |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
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存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |