RCC1 Pure 9/RCC1 50ug
货号：
610377 基本售价：
3726.0 元 规格：
50ug
产品信息
概述| 货号 | 610377 |
| 描述 | RCC1 (Regulator of Chromosome Condensation) is a chromatin-associated protein implicated in a number of cellular processes such as nuclei formation, initiation/termination of transcription, pre-mRNA splicing/3-end formation, mRNA export and DNA replication. Normally, RCC1 appears to play a structural role with chromatin. This nuclear protein can function as a guanine nucleotide exchange factor for the Ras-like GTPase, Ran/TC4. Loss of RCC1 expression is related to a structural transition of the chromosome and correlates with the inability of the cells to detect unreplicated DNA. RCC1 appears to be necessary for nucleocytoplasmic transport of precursors of spliceosomal small nuclear RNAs (snRNAs), intranuclear transport of U3 snRNA and processing of ribosomal RNAs, but not for export of transfer RNAs. |
| 别名 | Regulator of Chromosome Condensation-1 |
| 同种亚型 | IgG1 |
| 反应种属 | Human (QC Testing) Dog (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IHC, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human RCC1 aa. 19-176 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
