RPTP Alp Pure 21 50ug
货号：
610348 基本售价：
3726.0 元 规格：
50ug
产品信息
概述| 货号 | 610348 |
| 描述 | Receptor-like protein tyrosine phosphatases (RPTPs) represent an importantpathway for signal transduction via modification of protein tyrosine phosphorylation status. RPTPα is widely expressed and is particularly abundant in brain. Structurally, it is typical of RPTPs in that it has an intracellular region containing two tandem catalytic domains linked to a transmembrane and an extracellular region. However, unlike many RPTPs, the extracellular region of RPTPα is small (123 residues) and lacks any obvious structural motifs, though the protein is known to be heavily glycosylated. Both catalytic domains of RPTPα have intrinsic in vitro activity, but their exact roles in vivo remain uncertain. It has been postulated that due to their transmembrane nature, RPTPs are initiators for a cascade of intracellular signaling events, much like receptor tyrosine kinases. |
| 同种亚型 | IgM |
| 反应种属 | Human (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human RPTPα aa. 244-503 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
