RBP Pure 42/RBP 50ug
货号：
610237 基本售价：
3726.0 元 规格：
50ug
产品信息
概述| 货号 | 610237 |
| 描述 | Retinol, a metabolic precursor of retinal and retinoic acid, is transported in plasma bound to a carrier protein known as retinol-bindingprotein (RBP). RBP is the only retinoid-specific binding protein that has been identified in plasma. The presence of RBP increases the stability of retinol as it is transported from its stores to target cells. In plasma, the 21 kDa RBP forms a tight complex with thyroxine-binding transthyretin (TTR), a homotetramer of about 55 kDa. Association of RBP with TTR increases the stability of the retinol-RBP complex. It is believed that this association prevents filtration of the relatively small RBP through the kidney glomeruli. Once retinol is delivered to its target cells, the resulting retinol-free RBP has a reduced affinity for TTR and thus can be selectively cleared from the circulation by filtration through kidney glomeruli. The three dimensional structures of human and bovine RBP have been compared and appear to be very similar. |
| 同种亚型 | IgG1 |
| 反应种属 | Dog (QC Testing) Human, Mouse, Rat, Chicken (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IHC, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human RBP aa. 1-135 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
