Psme3 Pure 47/Psme3 50ug
货号：
611180 基本售价：
3690.0 元 规格：
50ug
产品信息
概述| 货号 | 611180 |
| 描述 | The 20S proteasome is the major constituent of the proteasomal complex that mediates degradation events, including the generation of antigenic peptides that interact with MHC class I. The 20S proteasome is a cylindrical shaped complex composed of four layers of rings, each with seven subunits. The inner rings contain α -subunits, while the outer rings contain β -catalytic subunits. The constituents of the PA28 activator complex are additional subunits with specialized roles in class I-mediated antigen presentation. PA28 is a ring-shaped structure with alternating α - and β -subunits. This complex binds the α -rings of 20S and stimulates its activity. Expression of the PA28 α - and β -subunits is strongly induced by IFN- γ . The protein product of the Psme3 gene, also known as the Ki antigen, is highly homologous to the PA28 α - and β -subunits and has been designated the PA28 γ -subunit. This protein forms a homohexamer that binds the 20S proteasome and is thought to modulate proteasome activity. The PA28 α - and β -subunits are located in the cytoplasm and in the nucleus, while the γ -subunit is almost exclusively nuclear. |
| 别名 | PA28-γ |
| 同种亚型 | IgG1 |
| 反应种属 | Rat (QC Testing) Human, Mouse, Dog (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse Psme3/PA28-γ aa. 45-147 |
| 存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
