Laminin B2 Pure 22/Laminin 50ug
货号:
610722 基本售价:
3690.0 元 规格:
50ug
产品信息
概述货号 | 610722 |
描述 | The basal lamina contains Collagen Type IV, proteoglycans, and glycoproteins. Laminin is a high molecular weight ( ≈850 kDa) oligomer, consisting of three different chains (A, B1, and B2) joined by disulfide bonds. The overall structure predicts two helical domains (I&II) at the COOH-terminal, cysteine-rich repeats (III&V), and two globular domains (IV&VI). Domains IV and VI are the binding sites for collagen and heparan sulfate, respectively. Several isoforms have been identified for the genes of each chain. Laminin B2 is 1576 amino acids plus a 33 amino acid signal peptide, 14 glycosylation sites, and 12 cysteine repeat domains. The expression of the Laminin subunits is detected rapidly during development and tissue regeneration. Attachment of cells to the basal lamina affects mitogenesis, motility, and differentiation. |
同种亚型 | IgG1 |
反应种属 | Human (QC Testing) Rat, Rabbit (Tested in Development) |
来源宿主 | Mouse |
使用方法 | WB, IF |
性能供应商 | BD Pharmingen |
免疫原 | Human Laminin B2 aa. 506-691 |
存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |