KAP Pure 39KAP 50ug
货号:
610334 基本售价:
3690.0 元 规格:
50ug
产品信息
概述货号 | 610334 |
描述 | Proteins that associate with cyclin-dependent kinases may function in cell cycle regulation. Therefore, a two-hybrid screen system was used to isolate cDNA which encode proteins that can interact with Cdk2. One of these was the dual-specificity protein phosphatase known as KAP (Cd kassociatedp hosphatase). KAP contains the HCXXXXGR motif characteristic of protein tyrosine phosphatases. It utilizes substrates that contain either phosphotyrosine or phosphoserine residues. In addition to binding Cdk2, KAP also associates with Cdc2. KAP does not require a cyclin subunit for binding to Cdk2 and Cdc2. The association of KAP with these two Cdks suggests that KAP may play a role in cell cycle control, possibly by regulating the phosphorylation status of a cdk or of a Cdk-associated protein. |
同种亚型 | IgG1 |
反应种属 | Human (QC Testing) Mouse, Rat, Dog, Chicken, Frog (Tested in Development) |
来源宿主 | Mouse |
使用方法 | WB, IHC, IF, Bioimg |
性能供应商 | BD Pharmingen |
免疫原 | Human KAP aa. 1-212 |
存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |