| 货号 | MCA878G |
| 克隆号 | A57H |
| 同种亚型 | IgM |
| 反应种属 | Human |
| 来源宿主 | Mouse |
| 应用 | E, H, WB |
| 供应商 | Bio-Rad Antibodies |
| 运输条件 | |
| 存放说明 | Store at +4oC. DO NOT FREEZE. This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use. |
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Published customer image: Mouse anti Human IgG (CH3 domain) antibody, clone A57H used as a coating antibody in a capture ELISA for vaccibodies contaiing the IgG (CH3 domain). Image caption: Characterization of fusion vaccines used in this study. (A) Schematic structure of a homodimeric vaccine fusion protein (Vaccibody, VB). Targeting, dimerization and antigenic units are indicated, as are the different moieties expressed in the various units. MHC class II targeted (I-Ed-specific) and non-targeted (NIP-specific) constructs are denoted (FvI-EFvPn)2< and (FvNIPFvPn)2, respectively, whereas LD78β VB are denoted (LD78βFvPn)2. where Pn indicates patient number. (B) Detection of VB proteins in supernatants of transfected HEK 293E cells in an ELISA specific for hγCH3. (C) Binding of MHC class II-targeted VB to I-Ed+ A20 cells. (D) LD78β VB displays dose-dependent chemotactic activity on lymphocytic Esb/MP cells. Recombinant LD78β was used as positive control. From: Ruffini PA, Os A, Dolcetti R, Tjønnfjord GE, Munthe LA, Bogen B. Targeted DNA vaccines eliciting crossreactive anti-idiotypic antibody responses against human B cell malignancies in mice. J Transl Med. 2014 Jul 25;12:207. |
