概述| 货号 | RDC1286 |
| 别名 | EC 2.7.10; EC 2.7.10.1; FLT4; Flt-4; fms-related tyrosine kinase 4; LMPH1A; PCLFLT41; soluble VEGFR3 variant 1; soluble VEGFR3 variant 2; soluble VEGFR3 variant 3; Tyrosine-protein kinase receptor FLT4; vascular endothelial growth factor receptor 3; VEGFR-3; VEGFR3Fms-like tyrosine kinase 4 |
全称 | Vascular Endothelial Growth Factor Receptor 3 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 2324 (Human); 14257 (Mouse) |
| 背景 | VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Airway Inflammation and Remodeling
- Endothelial Cell Markers
- Endothelial Progenitor and Endothelial Cell Markers
- Endothelial Progenitor Cell Markers
- ICC / IHC Images: VEGF R3/Flt-4
- Mini-review: Vascular Endothelial Growth Factor (VEGF)
- Platelets
- Proliferation Bioassay HUVECs
- Receptor Tyrosine Kinases (RTKs)
- Receptor Tyrosine Kinases (RTKs) in the Akt Pathway
- Receptors in the Jak/STAT Pathway
- VEGF Family
- VEGF R3 Marks a New Class of Endothelial Stem Cell
|
