概述| 货号 | RDC1533 |
| 别名 | CDLS2; DXS423ESMC1 structural maintenance of chromosomes 1-like 1 (yeast); KIAA0178DKFZp686L19178; SB1.8; SB1.8MGC138332; segregation of mitotic chromosomes 1; SMC protein 1A; SMC1 (structural maintenance of chromosomes 1, yeast)-like 1; SMC1 structural maintenance of chromosomes 1-like 1; SMC1A; SMC-1A; SMC-1-alpha; SMC1L1; SMC1SMC1alpha; Smcb; structural maintenance of chromosomes 1A; structural maintenance of chromosomes protein 1A |
全称 | Structural Maintenance of Chromosomes 1 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 8243 (Human); 63996 (Rat) |
| 背景 | The ATM protein kinase phosphorylates SMC1 protein in cells exposed to genotoxins. Overexpression of a non-phosphorylatable mutant of SMC1 subjects a cell to a defective S phase checkpoint and decreased cell survival in response to genotoxic stress. In cells expressing this mutant, BRCA1 and Nbs1 are still phosphorylated, suggesting that SMC1 phosphorylation is downstream of these other phosphorylation events. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Cell Cycle
- Cell Structure and Signaling Molecules
- Checkpoint
- DNA Damage and Repair
|
