货号 | RDC1953 |
别名 | FLJ12795; FLJ13221; FLJ25756; IGDCC5; immunoglobulin superfamily, DCC subclass, member 5; Protein Shen-Dan; protogenin homolog (Gallus gallus); Protogenin; PRTG; RPTG; Shen-Dan |
供应商 | R&D Systems |
Entrez Gene IDs | 283659 (Human); 235472 (Mouse); 315806 (Rat) |
背景 | Protogenin (Early/proto in expression, neogenin-like; also Prtg) is a 130 kDa (predicted), type I transmembrane member of the DCC/Neogenin family of proteins. It is expressed in mouse presomitic mesoderm, paraxial mesoderm, and neural tube. Mature mouse protogenin is 1168 amino acids (aa) in length. It contains a 920 aa extracellular domain (ECD) (aa 24 - 943) plus a 224 aa cytoplasmic region. The ECD contains four consecutive Ig-like domains (aa 24 - 405), followed by five sequential fibronectin type III domains (aa 413 - 908). The ECD of mouse protogenin shares 98%, 87% and 93% aa identity with the ECD of rat, chick and human protogenin, respectively. |
运输条件 | Blue Ice |
存放说明 | -20℃ |