概述货号 | RDC1713 |
别名 | BAG; Brain Tumor Associated Protein LRRC4; Brain Tumor-Associated Protein BAG; Leucine Rich Repeat Containing 4; Leucine-Rich Repeat-Containing 4; Leucine-Rich Repeat-Containing Protein 4; LRRC4; NAG14; Nasopharyngeal Carcinoma-Associated Gene 14 Protein; Netrin-G2 Ligand; NGL-2 |
全称 | Leucine-rich Repeat Containing 4 |
性能供应商 | R&D Systems |
Entrez Gene IDs | 64101 (Human); 192198 (Mouse); 641521 (Rat) |
背景 | LRRC4 (Leu-rich repeat/LRR-containing glycoprotein 4), LRRC4B and LRRC4C, also called NGL-2 (netrin-G ligand-2), NGL-3 and NGL-1, respectively, are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. Mature LRRC4 family members are type I transmembrane proteins with an extracellular region that contains nine LRRs, a C2-type Ig-like domain, and a Thr-rich segment. LRRC4 family members share ~55% aa identity, but each recognizes different ligands. LRRC4 and LRRC4C recognize Netrin-G2 and Netrin-G3, respectively, while LRRC4B recognizes the receptor tyrosine phosphatases LAR/PTPRF, PTPR delta and PTPR sigma. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - Cancer Biomarkers
- Cell Cycle
- ICC / IHC Images: LRRC4
- Immunoglobulin-Like Domain Transcription Factors
- NFkB Pathway
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