Human Endosialin/CD248 (NP_065137) VersaClone cDNA (10 UG)
货号：
RDC1825 基本售价：
7078.9 元 规格：
10 ug
产品信息
概述| 货号 | RDC1825 |
| 别名 | 2610111G01Rik; CD164 sialomucin-like 1; CD164L1; CD248 antigen; CD248 antigen, endosialin; CD248 molecule, endosialin; CD248; Endosialin; MGC119479; TEM1; TEM1MGC119478; Tumor endothelial marker 1 |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 57124 (Human); 70445 (Mouse); 293669 (Rat) |
| 背景 | Endosialin, also known as CD248 and tumor endothelial marker 1 (Tem1), is a 165 kDa transmembrane O-glycosylated protein that contains one C-type lectin, one Sushi, one EGF-like domain and a mucin-like stalk in its extracellular domain (ECD). It is expressed on activated perivascular and stromal cells in embyronic and tumor neovasculature but is downregulated in quiescent vasculature. Endosialin regulates pericyte proliferation, migration, and adhesion to matrix Fibronectin and Collagens I and IV. It is also required for lymph node and spleen remodeling during immune responses. Within the ECD, mouse Endosialin shares 76% and 93% aa sequence identity with human and rat Endosialin, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Adhesion Molecules on Endothelial Cells
- Cancer Biomarkers
- Endothelial Cell Markers
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