概述| 货号 | RDC0208 |
| 别名 | egf-like module containing, mucin-like, hormone receptor-like 4 pseudogene; egf-like module containing, mucin-like, hormone receptor-like 4; Egf-tm7; EMR4EGF-like module receptor 4; Fire; Gpr127; GPR127G-protein coupled receptor 127; G-protein coupled receptor PGR16; PGR16; PGR16G protein-coupled receptor 127 |
全称 | EGF-like Module Containing, Mucin-like, Hormone Receptor-like 4 | | 反应种属 | Mouse |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 326342 (Human); 52614 (Mouse) |
| 背景 | EMR4 cDNA encodes a predicted 689-amino acid protein containing two epidermal growth factor (EGF)-like modules, a mucin-like spacer domain, and a seven-transmembrane domain with a cytoplasmic tail. EMR4 was found to undergo proteolytic processing within the extracellular stalk region resulting in two protein subunits associated noncovalently as a heterodimer. It is predominantly expressed on resident macrophages. However, a much lower expression level was also detected in thioglycollate-elicited peritoneal neutrophils and bone marrow-derived dendritic cells. EMR4 is the first EGF-TM7 receptor known to mediate the cellular interaction between myeloid cells and B-cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Adhesion G Protein-Coupled Receptors
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