概述| 货号 | RDC1173 |
| 别名 | ADAP; Adhesion and degranulation promoting adaptor protein; adhesion and degranulation-promoting adaptor protein; FYB-120/130SLAP-130FYN-binding protein (FYB-120/130); FYN binding protein; FYN-binding protein; FYN-T-binding protein; p120/p130; PRO0823; SLAP130; SLP-76-associated phosphoprotein |
全称 | FYN Binding Protein (FYB-120/130) | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 2533 (Human); 23880 (Mouse); 499537 (Rat) |
| 背景 | FYB, also known as ADAP and SLAP130, is a 130 kDa hematopoietic-specific adaptor protein which contains an SH3-VASP homology 1 domain. It associates with other cytoplasmic proteins such as SH2-containing Leukocyte Phosphoprotein of 76 kDa (SLP-76). SLAP130 is phosphorylated in response to TCR/CD3 stimulation, and regulates the stability of SKAP55. A SLAP130:SKAP55 signaling module stimulates beta 1 and beta 2 integrin activation and promotes T cell-DC cell interaction. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
