Human TLR8 (NP 619542) VersaClone cDNA (10 UG)
货号：
RDC0712 基本售价：
7078.9 元 规格：
10 ug
产品信息
概述| 货号 | RDC0712 |
| 别名 | CD288 antigen; CD288; MGC119599; MGC119600; toll-like receptor 8 |
全称 | Toll-like Receptor 8 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 51311 (Human); 170744 (Mouse) |
| 背景 | TLRs make up a family of pattern recognition receptors that play important roles in the innate immune response. Broad classes of pathogens (e.g. viruses, bacteria, and fungi) constitutively express a set of mutation-resistant molecules called pathogen-associated molecular patterns (PAMPs). These microbial molecular markers may be composed of proteins, carbohydrates, lipids, nucleic acids and/or combinations thereof. Individual TLRs recognize distinct pathogen-associated PAMPs, initiating signaling cascades that promote the immune response. Structurally, TLRs are type I transmembrane receptors that possess varying numbers of extracellular N-terminal leucine-rich repeat (LRR) motifs, followed by a cysteine-rich region, a TM domain, and an intracellular Toll/IL-1 R (TIR) motif. The TIR motif is common to the larger IL-1 R/TLR superfamily. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - BIObrief: Pattern Recognition Receptors & the Innate Immune Response
- IL-1 Family
- Innate Immunity and the Toll-like Receptor Family
- Interactive Pathway: Inflammasome Activation Pathways
- Interactive Pathway: Toll-Like receptor Signaling Pathways
- Macrophage Activation Markers
- Mini-review: The Toll-like Receptor Family
- Neuroinflammation
- NFkB Pathway
- NOD-like Receptors and the Inflammasome
- Parturition & Surfactant Protein A
- Pattern Recognition Receptors
- T Cell Antigen Recognition
- TLR4: Contributing to Metabolic Syndrome in Multiple Tissues
- Toll-Like Receptors
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