概述| 货号 | RDC1089 |
| 别名 | FLJ14594; LERN1; LERN1UNQ201; leucine rich repeat and Ig domain containing 1; leucine rich repeat neuronal 6A; Leucine-rich repeat and immunoglobilin domain-containing protein 1; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A; LRRN6A; LRRN6Aleucine-rich repeat neuronal 6A; MGC17422 |
全称 | Leucine-rich Repeat And Ig Domain Containing Nogo Receptor-Interacting Protein 1 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 84894 (Human) |
| 背景 | LINGO-1 (Leucine-rich repeat- and Ig domain-containing nogo receptor-interacting protein 1) is a transmembrane protein of the leucine-rich repeat (LRR) family, ribonuclease inhibitor subfamily. The four known LINGO proteins contain LRR and IgCAM domains in the extracellular portion and share 44-61% aa identity. LINGO-1 is restricted to the nervous system and is concentrated in the brain as a component of the NgR1/p75 and NgR1/Taj (Troy) signaling complexes. LINGO-1 negatively regulates neurite outgrowth and myelination, and is highly conserved, showing 99% aa identity between human, mouse and rat. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Glial Lineage Markers
- Neurotrophin/Trk Family
- Nogo Proteins and Receptors
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