Human FoxP2 (NP 055306) VersaClone cDNA ( )
货号：
RDC1704 基本售价：
7078.9 元 规格：
10 ug
产品信息
概述| 货号 | RDC1704 |
| 别名 | CAG repeat protein 44; CAGH44; CAGH44TNRC10forkhead box protein P2; DKFZp686H1726; forkhead box P2; forkhead/winged-helix transcription factor; SPCH1; TNRC10; trinucleotide repeat containing 10; Trinucleotide repeat-containing gene 10 protein |
全称 | Forkhead Box P2 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 93986 (Human); 114142 (Mouse); 500037 (Rat) |
| 背景 | FoxP2 (Forkhead box protein P2; also CAGH44) is an 85-95 kDa member of the winged helix transcription factor gene family. It is a transcriptional repressor that is expressed principally in gut and lung epithelium, and in neurons involved in speech and language. Human FoxP2 is 715 amino acids (aa) in length. It contains a huge poly-Gln region (aa 123-231), a C2H2 Zn-finger domain (aa 346-371), a Leu-zipper segment (aa 388-409) and a forkhead DNA binding domain (aa 504-594). FoxP2 both homodimerizes and heterodimerizes with FoxP1 and P4, and binds CTBP1. There are multiple splice variants. There is an alternate start site at Met93, an 11 aa substitution for aa 57-715, a 25 aa insert after Gln86, an 11 aa substitution for aa 133-715, and a ten aa substitution for aa 423-715. Over aa 587-715, human and mouse FoxP2 are (100%) identical in aa sequence. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Forkhead Domain Transcription Factors
- ICC / IHC Images: FoxP2
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