Human DLL1 (NP 005609) VersaClone cDNA (10 UG)
货号:
RDC1045 基本售价:
7078.9 元 规格:
10 ug
产品信息
概述货号 | RDC1045 |
别名 | delta (Drosophila)-like 1; Delta 1; Delta; Delta1; delta-like 1 (Drosophila); delta-like protein 1; DL1; Drosophila Delta homolog 1; H-Delta-1 |
全称 | Delta-like 1 | 反应种属 | Human |
性能供应商 | R&D Systems |
Entrez Gene IDs | 28514 (Human); 13388 (Mouse); 84010 (Rat) |
背景 | DLL1 (Delta-like protein 1) is a transmembrane glycoprotein in the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. It plays a role in central nervous system morphogenesis, intervertebral joint formation, inner ear hair cell development and patterning, and arteriogenesis. It regulates the homeostasis and differentiation of neural, pancreatic, and myogenic progenitor cells, T and B lymphocytes. DLL1 is overexpressed in a number of cancers and contributes to tumorigenesis. The extracellular region of DLL1 can be shed from the cell surface, and the intracellular domain can be cleaved by gamma-secretase to translocate to the nucleus and regulate gene transcription. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - ICC / IHC Images: DLL1
- Notch Family
- Notch Pathway
- Somite Markers
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