概述| 货号 | RDC1218 |
| 别名 | BMP type II receptor; BMP type-2 receptor; BMPR2; BMPR-2; BMPR3; BMPR-IIprimary pulmonary hypertension 1; Bone morphogenetic protein receptor type II; bone morphogenetic protein receptor type-2; bone morphogenetic protein receptor, type II (serine/threonine kinase); BRK-3; EC 2.7.11; EC 2.7.11.30; FLJ41585; FLJ76945; PPH1BMR2; T-ALK; type II activin receptor-like kinase; type II receptor for bone morphogenetic protein-4 |
全称 | Bone Morphogenetic Protein Receptor II | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 659 (Human); 12168 (Mouse) |
| 背景 | Cellular responses to bone morphogenetic proteins (BMPs) are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. There are seven known type I serine/threonine kinases and five mammalian type II serine/threonine kinase receptors that function in TGF-beta superfamily signal transduction. The type II receptors for TGF-beta and activin bind ligands with high affinity by themselves. In contrast, BMPR-II binding to BMP-2, BMP-4, and BMP-7 is facilitated by the presence of the type I receptor. The type I receptors are also known as activin receptor-like kinases or ALKs. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - BMP Family
- BMPs
- Cytokines in the Nervous System
- ICC / IHC Images: BMPR-II
- Mesenchymal Stem Cell Markers
- Mini-review: Bone Morphogenetic Proteins (BMPs)
- TGF-beta Superfamily
|
