Human CD98 (NP 001012680) VersaClone cDNA (10 UG)
货号：
RDC0463 基本售价：
7078.9 元 规格：
10 ug
产品信息
概述| 货号 | RDC0463 |
| 别名 | 4F2; 4F2hc; 4T2HC; antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43,4F2HC; CD98 antigen; CD98 heavy chain; CD98; CD98HC; heavy chain; Lymphocyte activation antigen 4F2 large subunit; MDU1antigen defined by monoclonal 4F2, heavy chain; monoclonal 44D7; NACAE4F2 cell-surface antigen heavy chain; SLC3A2; solute carrier family 3 (activators of dibasic and neutral amino acidtransport), member 2,4F2 heavy chain antigen |
| 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 6520 (Human); 17254 (Mouse) |
| 背景 | CD98, also known as 4F2, is a widely expressed disulfide-linked heterodimer in the solute transporter family. It consists of an 85 kDa glycosylated type II transmembrane heavy chain and a 40-50 kDa non-glycosylated light chain with 12 transmembrane segments. The heavy chain (SLC3A2) pairs with one of several light chains (SLC7A5, 6, 7, 8, 10, or 11) and is required for the cell surface expression and amino acid transport function of the light chains. CD98 also mediates integrin signaling, T cell costimulation, B cell proliferation, and viral fusion with cell membranes. Within the extracellular region, human CD98 heavy chain shares 73% and 71% aa sequence identity with mouse and rat CD98 heavy chain, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Cancer Biomarkers
- Human CD Marker Products
- Solute Carrier Family (SLC)
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