概述| 货号 | RDC0281 |
| 别名 | nAchRa4; BFNC; cholinergic receptor, nicotinic, alpha 4; cholinergic receptor, nicotinic, alpha polypeptide 4; CHRNA4; EBN; EBN1; ENFL1; FLJ95812; nAChR alpha 4; NACHR; NACHRA4; NACRA4; neuronal acetylcholine receptor subunit alpha-4; neuronal nicotinic acetylcholine receptor alpha-4 subunit |
全称 | Nicotinic Acetylcholine Receptor alpha 4 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 1137 (Human); 11438 (Mouse); 25590 (Rat) |
| 背景 | CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. CHRNA4 is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in CHRNA4 cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in CHRNA4 that provide protection against nicotine addiction have been described. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Neurotransmitter Receptors
- Neurotransmitter Receptors, Transporters, and Ion Channels
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