Human Common beta Chain (NP 000386) VersaClone cDNA (10 UG)
货号：
RDC1170 基本售价：
7078.9 元 规格：
10 ug
产品信息
概述| 货号 | RDC1170 |
| 别名 | beta, low-affinity; CD131 antigen; CD131; CDw131; colony stimulating factor 2 receptor, beta, low-affinity(granulocyte-macrophage); CSF2RB; cytokine receptor common subunit beta; GM-CSF R beta; GM-CSF/IL-3/IL-5 receptor common beta subunit; GM-CSF/IL-3/IL-5 receptor common beta-chain; IL-3 R beta; IL3RB; IL-5 R beta; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3receptor, beta (high affinity) |
| 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 1439 (Human); 12983 (Mouse) |
| 背景 | The high-affinity receptors for Interleukin-3 (IL-3), IL-5, and Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) consist of a cytokine-specific a chain, and a shared common beta chain subunit (CD131) that is essential for receptor signaling. CD131 also associates with the receptor for Erythropoietin, forming a tissue-protective heteroreceptor complex. Phosphorylation of CD131 following receptor activation imparts growth and survival signals to the responding hematopoietic cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Common beta Chain Receptor Family
- Cytokines and Receptors in Allergy and Asthma
- Cytokines and Receptors in Tfh Cell Differentiation and Function
- Human CD Marker Products
- Mini-review: Interleukin 5
- Monocyte Markers
- Receptors in the Jak/STAT Pathway
|
