Human Androgen R/NR3C4 (NP 000035) VersaClone cDNA (10 UG)
货号:
RDC1285 基本售价:
7078.9 元 规格:
10 ug
产品信息
概述货号 | RDC1285 |
别名 | AIS; androgen receptor; AR; DHTR; DHTRTFM; Dihydrotestosterone receptorHYSP1; HUMARA; NR3C4; NR3C4KD; Nuclear receptor subfamily 3 group C member 4; SBMA; SMAX1; SMAX1SBMA; spinal and bulbar muscular atrophy |
全称 | Androgen Receptor | 反应种属 | Human |
性能供应商 | R&D Systems |
Entrez Gene IDs | 367 (Human) |
背景 | Human Androgen Receptor (AR; NR3C4) is a 110 kDa member of the NR3 subfamily of the nuclear hormone receptor family. Androgen receptors are expressed by androgen-sensitive tissue (bone, prostate, testis) and exist as both ahomodimers and a heterodime in a complex with the glucocorticoid receptor. Multiple forms of the androgen receptor are known to exist. The 110 kDa B form is 919 amino acids in length. Phosphorylation increases its molecular weight to 112 kDa and 114 kDa. A five amino acid deletion (amino acids 74 - 78) in AR-B has been reported. In addition, a short A form of 87 kDa and 732 amino acids is also known. Expanded polyglutamine repeats in the androgen receptor are known to cause Kennedys disease, an X-linked form of motor neuron disease. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - Cancer Stem Cell Transcription Factors
- ICC / IHC Images: Androgen R/NR3C4
- Nuclear Hormone Receptors and Regulators
- Steroid Hormones and Bioactive Lipids
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