| 货号 | 61486 |
| 同种亚型 | IgG |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | Western Blot |
| 使用方法 | Validated Applications: WB: 1:500 - 1:2,000 dilution |
| 供应商 | Active Motif |
| 纯化方式 | Affinity Purified |
| 免疫原 | This antibody was raised against a peptide within the C-terminal region of human WDR5. |
| 背景 | WDR5 (WD repeat-containing protein 5) is a component of the Set1 histone methyltransferase / MLL1/MLL complex that is involved in methylation and dimethylation of Lys-4 of Histone H3. H3K4 methylation represents a specific tag for epigenetic transcriptional activation. WDR5 is also a component of the NSL complex and it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. WDR5 is also core component of other methyltransferase-containing complexes including MLL2/3 (also named ASCOM complex) and MLL4/WBP7. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 40 kDa |
| 参考文献 |
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WDR5 antibody (pAb) tested by Western blot. Nuclear extract (30 µg) of Raji (Lane 1) and HeLa cells (Lane 2) probed with WDR5 antibody (pAb) at a 1:500 dilution. |
