货号 | 61184 |
同种亚型 | IgG |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | Immunofluorescence/Immunocytochemistry |
使用方法 | Validated Applications: ICC/IF: 1 - 2 µg/ml dilution |
供应商 | Active Motif |
纯化方式 | Protein A Chromatography |
免疫原 | This CENP-B antibody was raised against a recombinant protein corresponding to the C-terminal region of human CENP-B. |
背景 | CENP-B (Centromere protein B) is a protein associated with centromeric DNA and crucial to the formation of the special chromatin structure on the α-satellite DNA repeats of the human centromere. CENP-B specifically binds a 17 bp sequence which may function as a cis-element for centromere-specific nucleosome assembly. CENP-B plays a role in the organization of centromere satellite DNA into a higher order structure, directing centromere formation and kinetochore assembly in mammalian chromosomes. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -80°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified rabbit IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 67 kDa |
参考文献 |
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CENP-B pAb tested by immunofluorescence. Staining of HeLa cells with CENP-B pAb at a 1 µg/ml dilution (green) and α-tubulin (red, Catalog No. 39527) at 1 µg/ml. |