HL-60 nuclear extract
货号：
36072 基本售价：
2465.0 元 规格：
200 ug
产品信息
概述| 货号 | 36072 |
| 使用方法 | HL-60 nuclear extract is recommended for use in studies related to 1) myeloid differentiation, 2) hematopoiesis, and 3) acute promyelocytic leukemia. |
性能| 供应商 | Active Motif |
| 背景 | HL-60 nuclear extract was prepared from a cell culture of the human promyelocytic leukemia HL-60 cell line. The HL-60 cell line was originally derived from tumor tissue obtained from a 36 year old female patient with acute promyelocytic leukemia. HL-60 cells are primarily neutrophilic myelocyte precursors in morphology and can be induced to differentiate into granulocytic, monocytic, macrophage-like and eosinophil phenotypes depending on the compound treatment. These cells require insulin and transferrin for growth. In research, HL-60 cells are most commonly used to study myeloid differentiation, hematopoiesis, and acute promyelocytic leukemia. Historically, this cell line was used as a model system to study the effect of DNA topoisomerase IIα and IIβ on differentiation and apoptosis of cells. |
| 运输条件 | Dry Ice |
| 存放说明 | To ensure stability, extracts should be stored at -80°C.
We recommend aliquoting the extracts into single-use fractions and then storing them at -80°C. This eliminates repeated freeze/thaw cycles. |
| 外观 | 200 µg of HL-60 nuclear extract at 7.72 µg/µl. |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
参考图片Figure 1: Monitoring AML-1/Runx1 activation with the TransAM AML-1/Runx1 Kit.
Increasing amounts of nuclear extract from unstimulated HeLa and HL-60 cells are tested for AML-1/Runx1 activation using the TransAM AML-1/Runx1 Kit. |
