| 货号 | 36017 |
| 使用方法 | MCF-7 nuclear extract is specifically recommended for studies related to breast cancer research. |
| 供应商 | Active Motif |
| 背景 | MCF-7 nuclear extract was prepared from cell cultures of the human MCF-7 breast adenocarcinoma cancer cell line. The MCF-7 cell line was originally derived from a pleural effusion of a 69-year old Caucasian woman with metastatic breast cancer. MCF-7 cells are the best characterized and most commonly utilized cell lines in in vitro breast cancer studies. The MCF-7 cell line has retained several characteristics that are particular to mammary epithelium, including the ability to grow as a monolayer, form domes, and respond to hormones. These cells also display a low metastatic potential, leading to the assumption that they represent an early epithelial adenocarcinoma phenotype. These characteristics make MCF-7 cells an ideal model system to study malignant progression in relation to breast cancer. |
| 运输条件 | Dry Ice |
| 存放说明 | To ensure stability, extracts should be stored at -80°C. We recommend aliquoting the extracts into single-use fractions and then storing them at -80°C. This eliminates repeated freeze/thaw cycles. |
| 外观 | 2 x 100 µg of MCF-7 nuclear extract at 2.5 µg/µl. |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
Figure 1: Monitoring ERα activation with the TransAM ER Kit. Different amounts of untreated and H2O2 post-treated nuclear extracts from MCF-7 cells are tested for ER activity using the TransAM ER Kit. | |
Figure 1: Monitoring Sp1 and Sp3 activity with the TransAM Sp1/Sp3 Kit. Different amounts of untreated and H2O2-post treated nuclear extracts from MCF-7 cells are tested for Sp1 and Sp3 activity using the TransAM Sp1/Sp3 Kit. |
