| 货号 | 71652S |
| 供应商 | CST |
| 背景 | Protein kinase C (PKC) family members are involved in a number of signal transduction processes including secretion, gene expression, proliferation, and muscle contraction and many PKC substrates continue to be unidentified (1,2). Isozymes of PKC are subdivided into conventional PKCs (cPKC), novel PKCs (nPKC), and atypical PKCs (aPKC). PKCα, βI, βII, and γ isoforms belong to the cPKC group (1). When activated, cPKC isozymes phosphorylate substrates containing Ser or Thr, with Arg or Lys at the -3, -2, and +2 positions, and a hydrophobic amino acid at position +1 (1-3). |
| 存放说明 | -20C |
| 参考文献 | 1 . Pearson, R.B. and Kemp, B.E. (1991) Methods Enzymol 200, 62-81. 2 . Obata, T. et al. (2000) J Biol Chem 275, 36108-15. 3 . Nishikawa, K. et al. (1997) J Biol Chem 272, 952-60. |
