Recombinant PRDM14 protein
货号:
31397 基本售价:
6162.5 元 规格:
20 ug
产品信息
概述货号 | 31397 |
别名 | PFM11 |
使用方法 | Recombinant PRDM14 is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling. |
性能供应商 | Active Motif |
背景 | PRDM14 (PR Domain Containing 14) is a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. PRDM14 possesses histone methyltransferase activity. PRDM14 is a transcription factor that has both positive and negative roles on transcription. It is required for the maintenance of embryonic stem cell identity and the reacquisition of pluripotency in somatic cells. PRDM14 may play an essential role in germ cell development at two levels: the reacquisition of potential pluripotency, including Sox2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression. PRDM14 directly up-regulates the expression of pluripotency gene Oct4 through its proximal enhancer. PRDM14 binds to the DNA consensus sequence 5-GGTC[TC]CTAA-3. |
运输条件 | Dry Ice |
存放说明 | Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
外观 | Full length recombinant PRDM14 protein expressed in Sf9 cells at a concentration of 1 mg/ml in 25 mM HEPES, pH 7.5, 150 mM NaCl and 5% glycerol. |
声明本官网所有报价均为常温或者蓝冰运输价格,如有产品需要干冰运输,需另外加收干冰运输费。 |
参考图片Recombinant PRDM14 protein gel. PRDM14 protein was run on a 10% SDS-PAGE gel and stained with Coomassie blue. |