Recombinant PPARγ-LBD protein
货号:
31143 基本售价:
6162.5 元 规格:
10 ug
产品信息
概述货号 | 31143 |
别名 | GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma |
使用方法 | Recombinant PPARγ-LBD protein has been applied in Western blot (30 kDa), DNA and protein-protein interactions assays and can be used for ligand binding assays (20-100 ng) and protein-protein interactions assays (100 ng).
NOTE: The presence of Poly [d(I-C)] in buffers may affect protein functionality and should be avoided. |
性能供应商 | Active Motif |
背景 | Peroxisome Proliferator-Activated Receptors(PPARs) are nuclear receptors involved in lipid transport and metabolism. As such, their roles in chronic diseases such as diabetes, obesity, atherosclerosis and cancer are heavily investigated. Transcriptional activity of PPARs is regulated by fatty acid binding. Three PPAR isotypes have been identified: α, δ and ϒ.PPARγ stimulates lipolysis of circulating triglycerides and the subsequent uptake of fatty acids into adipose cells. PPARs bind to peroxisome proliferator response elements (PPREs) as heterodimers with the retinoid X receptor(RXR). |
运输条件 | Dry Ice |
外观 | 10 µg of Recombinant PPARγ-LBD protein and Dilution Buffer AM1 (20 mM Tris-Cl (pH 8), 20% glycerol, 100 mM KCl, 1 mM DTT and 0.2 mM EDTA). Protein is supplied at 0.4 µg/µl in Dilution Buffer AM1. |
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