| 货号 | 31489 |
| 别名 | Lysine Acetyltransferase 7, HBO1, HBOA, MYST2, Histone Acetyltransferase Binding To ORC1 |
| 使用方法 | Recombinant KAT7 protein is suitable for use in enzyme kinetics, inhibitor screening, and selectivity profiling. |
| 供应商 | Active Motif |
| 背景 | KAT7 (K(Lysine) Acetyltransferase 7) is a MYST-family histone acetyltransferase (HAT) that forms a complex with ING4/5, JADE1/2/3, and Eaf6, which is found enriched on coding regions of genes, supporting a role in transcriptional elongation. In addition, KAT7 is thought to participate in events controlling the initiation of DNA replication. |
| 运输条件 | Dry Ice |
| 存放说明 | Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 外观 | Full length recombinant KAT7 protein is supplied at a concentration of 0.6 µg/µl in 25 mM Hepes pH 7.5, 300 mM NaCl, 5% Glycerol, 0.04% Triton X-100, 0.2 mM TCEP, 0.2 mg/ml 3× Flag peptide. |
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Recombinant KAT7 protein gel. Recombinant KAT7 was run on an 8% SDS-PAGE gel and stained with Coomassie blue. | |
Recombinant KAT7 protein activity assay Recombinant KAT7 activity titration was assessed using a Radiometry assay. Titration curves were generated to show signal response in the presence of histone peptide substrate at increasing KAT7 concentrations. This data was generated and kindly provided courtesy of ChemPartner. |
