Recombinant BRPF1 (1077-1205), GST-tag
货号：
31484 基本售价：
5872.5 元 规格：
100 ug
产品信息
概述| 货号 | 31484 |
| 别名 | BR140, Peregrin |
| 使用方法 | Recombinant BRPF1 (1077-1205), GST-tag is suitable for use in binding assays, inhibitor screening, and selectivity profiling. |
性能| 供应商 | Active Motif |
| 背景 | Bromodomain and PHD finger containing (BRPF1) protein is a component of the MOZ/MORF complex which has histone H3 acetyltransferase activity. The bromodomain of BRPF1 recognizes acetylated histone lysine residues and function as a ‘reader’ of these epigenetic histone marks to regulate chromatin structure and gene expression by linking associated proteins to the recognized acetylated nucleosomal targets. BRPF1 is known to positively regulate the transcription of RUNX1 and RUNX2.BRPF1 possesses a PWWP (Pro-Trp-Trp-Pro) domain that functions in the association of PWWP domain-containing proteins with chromatin. PWWP domains have been shown to bind DNA and also specifically recognized methylated lysine residues of histones. In doing so they are suspected to be involved in the mediation of the cross-talk between DNA and histone epigenetic marks. Mutations in PWWP domains have been shown to be associated with various human diseases, including cancer. |
| 运输条件 | Dry Ice |
| 存放说明 | Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 外观 | Recombinant BRPF1 (1077-1205), GST-tag protein expressed in E. coli at a concentration of 2 mg/ml in 25 mM Tris pH 7.4, 150 mM NaCl and 5% glycerol. |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
参考图片Recombinant BRPF1 (1077-1205), GST-tag protein gel.
BRPF1 (1077-1205), GST-tag protein was run on an SDS-PAGE gel and stained with Coomassie blue. |
