Recombinant ASH1L (2407-2579) protein
货号：
31445 基本售价：
5872.5 元 规格：
100 μg
产品信息
概述| 货号 | 31445 |
| 别名 | ASH1; KMT2H; ASH1L1 |
| 使用方法 | Recombinant ASH1L (2407-2579) is suitable for use in binding assays, inhibitor screening, and selectivity profiling. |
性能| 供应商 | Active Motif |
| 背景 | ASH1L is a member of the Trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. The bromodomain functions as a ‘reader’ of epigenetic histone marks and regulates chromatin structure and gene expression by linking associated proteins to the recognized acetylated nucleosomal targets. ASH1L is localized to the nucleus and also to cell-cell tight junctions where it is hypothesized to function in adhesion-mediated signaling. ASH1L functions in methylation of H3K4 and regulation of expression of HOX genes and may possess methyltransferase activity directed at H3K36. ASH1L has also been implicated in facioscapulohumeral muscular dystrophy. |
| 运输条件 | Dry Ice |
| 存放说明 | Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 外观 | 100 µg of recombinant ASH1L (2407-2579) protein expressed in E. coli at a concentration of 6.7 mg/ml in 25 mM HEPES pH 7.5, 150 mM NaCl and 5% glycerol. |
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参考图片Recombinant ASH1L (2407-2579) protein gel.
ASH1L (2407-2579) protein was run on a 10% SDS-PAGE gel and stained with Coomassie blue. |
