Recombinant DNMT3L protein
货号：
31414 基本售价：
5872.5 元 规格：
20 ug
产品信息
概述| 货号 | 31414 |
| 别名 | DNA Methyltransferase 3 Like, |
| 使用方法 | Recombinant DNMT3L protein is suitable for use in reconstituting DNMT3 complexs, functional studies. |
性能| 供应商 | Active Motif |
| 背景 | DNMT3L (DNA (Cytosine-5-)-Methyltransferase 3-Like) is a nuclear protein with similarity to the DNMT family of proteins, but does not function as a DNA methyltransferase. It serves as an essential regulator of DNMT3A and DNMT3B, recruiting them to sites for deposition of de novo DNA methylation. DNMT3L is expressed in the presumptive gametes in mammalian embryos and is required for the establishment of genomic imprinting. DNMT3L has a PHD-like domain that allows binding to chromatin through interactions with the amino terminal tail of histone H3 that is devoid of lysine 4 methylation. |
| 运输条件 | Dry Ice |
| 存放说明 | Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 外观 | Full length recombinant DNMT3L protein is supplied in 25 mM Tris pH 8.0, 300mM NaCl, 5% Glycerol and 0.04% Triton X-100, 1mM DTT. Please refer to product insert upon arrival for lot-specific concentration. |
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