Recombinant ERK2 protein
货号：
31153 基本售价：
5872.5 元 规格：
5 ug
产品信息
概述| 货号 | 31153 |
| 别名 | MAPK1, ERK, p38, p40, p41, ERT1, ERK-2, MAPK2, PRKM1, PRKM2, P42MAPK, p41mapk, p42-MAPK |
| 使用方法 | Recombinant ERK2 is suitable for kinase assays. The molecular weight of the protein is ~44.556 kDa. The activity of the protein is ~ 470,000 units/mg with 1 unit defined as the amount of enzyme that will catalyze the transfer of 1 pmol phosphate to myelin basic protein per minute at 30°C.
Recommended Kinase Reaction Buffer: 20 mM Tris-HCL, 25 mM β-glycerophosphate, 5 mM EGTA, 1 mM sodium orthovanadate and 1 mM DTT, pH 7.5.
Kinase activity may vary depending on the substrate and reaction conditions used. |
性能| 供应商 | Active Motif |
| 背景 | The extracellular signal-regulated kinases 1 and 2 (ERK1andERK2), also called p44 and p42 MAP kinases, are members of the Mitogen Activated Protein Kinase (MAPK) family of proteins found in all eukaryotes. Because the 44 kDa ERK1 and the 42 kDa ERK2 are highly homologous and both function in the same protein kinase cascade, the two proteins are often referred to collectively as ERK1/2 or p44/p42 MAP kinase. The ERK1/2 signaling cascade has been shown to be a critical regulator of cell differentiation, cell physiology and neuronal function. Aberrant control of ERK1/2 activity has been implicated in a variety of pathological conditions, including cancer and autoimmune diseases, and efficient study methods are in demand. |
| 运输条件 | Dry Ice |
| 存放说明 | Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 外观 | 5 µg of Recombinant ERK2 protein in 50 mM Tris-HCl, 150 mM NaCl, 1 mM DTT, 50% glycerol, pH 8.5. Please refer to product insert upon arrival for lot-specific concentration. |
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