Recombinant TBP protein
货号：
31246 基本售价：
5727.5 元 规格：
10 ug
产品信息
概述| 货号 | 31246 |
| 别名 | HDL4; GTF2D; SCA17; TFIID; GTF2D1 |
| 使用方法 | Recombinant TBP protein is suitable for use in in vitro transcription assays. A recommended starting point is 1-5 ng recombinant protein per reaction. |
性能| 供应商 | Active Motif |
| 背景 | TBP (also known as TATA box binding protein,GTF2D,transcription initiation factor TFIID TBP subunit,TATA-binding factor,TF2D,TFIIDorSCA17). RNA polymerase II is an enzyme found in eukaryotic cells composed of 12 subunits that catalyzes transcription of DNA. Transcription consists of three phases: initiation, elongation and termination. Transcription initiation involves TFIID, which is composed of TATA-binding protein (TBP) and TBP-associated factors (TAFs), as part of the RNA polymerase II pre-initiation complex (PIC). TBP binds to the TATA box sequence, which is located upstream of the transcription start site in some eukaryotic gene promoters, and helps position RNA polymerase II. TBP contains a string of glutamines at the N-terminus which affect DNA binding and the rate of transcription complex formation. TBP is also associated with RNA polymerase I and RNA polymerase III. |
| 运输条件 | Dry Ice |
| 外观 | 10 µg of recombinant protein supplied at a concentration of 0.1 µg/µl in 20 mM Tris-HCl, pH 7.3, 100 mM KCl, 0.2 mM EDTA and 20% glycerol. |
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