Recombinant SIRT1 (193-741) protein
货号：
31533 基本售价：
5872.5 元 规格：
100 ug
产品信息
概述| 货号 | 31533 |
| 别名 | Sirtuin 1, SIRT-1, SIR2-Like Protein, SIR2L1, SIR2alpha |
| 使用方法 | Recombinant SIRT1 protein is useful for histone deacetylase assays and the study of DNA Repair. |
性能| 供应商 | Active Motif |
| 背景 | SIRT1 (Sirtuin 1, SIR2L1) is a member of the Sirtuin family of proteins related to the yeast Sir2 protein. Like Sir2 and other Sirtuins, SIRT1 is an NAD+-dependent histone and protein deacetylase. SIRT1 catalyzes the removal of acetyl groups from a variety of protein substrates (NBS1, p53, Ku70, etc.) as well as from Histone H4 Lys16 (H4K16). SIRT1 is involved in the regulation of a number of cellular processes, including transcription, metabolism, DNA repair and aging, and increased SIRT1 is associated with extended lifespan of C. elegans. |
| 运输条件 | Dry Ice |
| 存放说明 | Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 外观 | Recombinant SIRT1 (193-741) protein is supplied in 25 mM Tris pH 8.0, 150 mM NaCl, 5% glycerol. Please refer to product insert upon arrival for lot-specific concentration. |
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