Recombinant SIRT6 protein
货号：
31532 基本售价：
5872.5 元 规格：
100 ug
产品信息
概述| 货号 | 31532 |
| 别名 | Sirtuin 6, Regulatory Protein SIR2 Homolog, SIR2-Like Protein 6, SIRT-6 |
| 使用方法 | Recombinant SIRT6 protein is useful for histone deacetylase assays and the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
性能| 供应商 | Active Motif |
| 背景 | SIRT6 (Sir2 homologue 6) is an NAD+ dependant histone deacetylase (HDAC) related to SIRT1 and to the yeast Sir2 protein. SIRT6, originally identified as a tubulin deacetylase, was recently found to be able to deacetylate histone H3 acetylated at lysine 9.
In vivo, acetylation is controlled by the antagonistic activities of histone acetyltransferases (HATs) and histone deacetylases (HDACs). The HDACs are grouped into four classes, on the basis of similarity to yeast counterparts: class I (HDAC1, HDAC2, HDAC3 and HDAC8), class II (HDAC4, HDAC5, HDAC6, HDAC7, HDAC9 and 10), class III (SIRT1-7) and class IV (HDAC11). |
| 运输条件 | Dry Ice |
| 存放说明 | Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 外观 | Full length recombinant SIRT6 protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 0.04% Triton X-100, 5% glycerol. Please refer to product insert upon arrival for lot-specific concentration. |
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