Cathepsin E Inhibitor Screening Kit (Fluorometric)
货号：
K166-100 基本售价：
9740.0 元 规格：
100assays
产品信息
概述| 货号 | K166-100 |
| 描述 | Cathepsin E (CTSE, EC: 3.4.23.34) is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that is found in highest concentration on the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of the gastric cancers. BioVision’s Cathepsin E Inhibitor Screening Kit utilizes the ability of Cathepsin E to cleave a synthetic MCA-based peptide substrate to release free MCA, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin E-specific inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the MCA fluorescence. This simple and high-throughput adaptable assay kit can be used to screen/study/characterize the potential inhibitors of Cathepsin E. |
| 同种亚型 | Rabbit IgG |
| 来源宿主 | Rabbit |
性能| 供应商 | Biovision |
| 检测类型 | Fluorescence (Ex/Em = 320/420 nm)• Applications - Screen/study/characterize potential inhibitors of Cathepsin E |
| 产品特色 | • Convenient & Rapid• High-throughput adaptable assay to screen/study/characterize the potential inhibitors of Cathepsin E• Cathepsin E inhibitor is included in the kit |
| 试剂盒组分 | • CTSE Assay Buffer• Human Cathepsin E• CTSE Substrate• CTSE Inhibitor (1 mM Pepstatin A in DMSO)• |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
