Cathepsin K Inhibitor Screening Kit (Fluorometric)
货号:
K150-100 基本售价:
6552.5 元 规格:
100assays
产品信息
概述货号 | K150-100 |
描述 | Cathepsin K (CTSK, EC 3.4.22.38), a lysosomal cysteine protease, is involved in osteoclastic bone remodeling and resorption. In addition, it also degrades collagen, gelatin and elastin. Biovision’s Cathepsin K Inhibitor Screening Kit utilizes the ability of active Cathepsin K to cleave the synthetic AFC based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin K-specific inhibitor, the cleavage of this substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This simple and high-throughput adaptable assay kit can be used to screen/study/characterize potential inhibitors of Cathepsin K. |
同种亚型 | Rabbit IgG |
来源宿主 | Rabbit |
性能供应商 | Biovision |
检测类型 | Fluorescence (Ex/Em = 400/505 nm• Applications - Screen/study/characterize potential inhibitors of Cathepsin K |
产品特色 | • Simple & convenient• High-throughput adaptable assay to screen/study/characterize the potential inhibitors of Cathepsin K• Cathepsin K inhibitor, FF-FMK is included in the kit |
试剂盒组分 | • CTSK Reaction Buffer• CTSK Reagent• Cathepsin K (Human)• CTSK Substrate, Ac-LR-AFC (10 mM)• CTSK Inhibitor (FF-FMK, 1 mM) |
运输条件 | Dry Ice |
存放说明 | -80℃ |
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