(±)11(12)-EET-d11
货号：
10006413-100ug 基本售价：
14784.0 元 规格：
100 ug
产品信息
概述| 货号 | 10006413-100ug |
| 描述 | (±)11(12)-EET-d11 contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of (±)11(12)-DiHETrE by GC- or LC-mass spectrometry. (±)11(12)-EET (Item No. 50511) is biosynthesized from arachidonic acid in rat and rabbit liver microsomes by CYP450.1,2 (±)11(12)-EET has been shown, along with (±)8(9)-EET (Item No. 50351), to play a role in the recovery of depleted Ca2+ pools in cultured smooth muscle cells.3 |
| 别名 | (±)11(12)-EpETrE-d11; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Chacos, N.,Falck, J.R.,Wixtrom, C., et al. Novel epoxides formed during the liver cytochrome P-450 oxidation of arachidonic acid. Biochemical and Biophysical Research Communications 104, 916-922 (1982).
2.Oliw, E.H.,Guengerich, F.P., and Oates, J.A. Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediates. The Journal of Biological Chemisty 257, 3771-3781 (1982).
3.Graber, M.N.,Alfonso, A., and Gill, D.L. Recovery of Ca2+ pools and growth in Ca2+ pool-depleted cells is mediated by specific epoxyeicosatrienoic acids derived from arachidonic acid. The Journal of Biological Chemisty 272, 29546-29553 (1997).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% deuterated forms (d1-d11) |
| 计算分子量 | 331.5 |
| 分子式 | C20H21D11O3 |
| 稳定性 | ≥ 1 year |
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