ORN R-2176-dT 1mg
货号：
130-104-437 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-104-437 |
| 描述 | TLR7 and TLR8 are members of the Toll-like-receptor (TLR) family, recognizing (virally derived) double- or single-stranded RNA, leading to activation of immune cells. ORN R-2176-dT activates both human TLR7 and TLR8 as well as murine TLR7 and induces a broad spectrum of cytokines from human PBMCs (IFN-α, IFN-γ, IL12, and TNF-α).4ORN R-2176-dT and ORN R-2176-dT Control can be used without a transfection reagent (e.g. DOTAP-Cl). |
性能| 供应商 | Miltenyi |
| 背景 | TLR7 and TLR8 are members of the Toll-like-receptor (TLR) family recognizing pathogen-associated molecular patterns.1,7 The natural ligands of TLR7 and TLR8, double- or single-stranded RNA, can be mimicked by short synthetic oligoribonucleotides (ORNs).2-5 RNA motifs activating either TLR7 or TLR8 only or both, TLR7 and TLR8, have been described. |
